According to statistics, below is the top 10 most common types of cancer diagnosed in U.S. women:
- Breast Cancer (117.7)
- Lung (and Bronchus) Cancer (54.2)
- Colon and Rectal Cancer (42.7)
- Corpus and Uterus, NOS (23.1)
- Non-Hodgkin Lymphoma (16.1)
- Skin Melanomas (14.0)
- Thyroid Cancer (13.8)
- Ovarian Cancer (12.5)
- Kidney and Renal Pelvis Cancer (10.0)
- Pancreatic Cancer (9.7)
A possible genetic contribution to both breast and ovarian cancer risk is indicated by the increased prevalence of these cancers among women with a family history . Additionally, about 5% to 10% of breast cancers are thought to be hereditary, caused by abnormal genes passed from parent to child.
Genes are particles in cells, contained in chromosomes, and made of DNA (deoxyribonucleic acid). DNA contains the instructions for building proteins, not to mention proteins control the structure and function of all the cells that make up your body. Furthermore, Everyone has BRCA1 and BRCA2 genes, and the function of these genes is to repair cell damage and keep breast cells growing normally. But when these genes contain abnormalities or mutations that are passed from generation to generation, the genes don't function normally and breast cancer risk increases. Abnormal BRCA1 and BRCA2 genes may account for up to 10% of all breast cancers, or 1 out of every 10 cases.
You are substantially more likely to have an abnormal breast cancer gene if:
- You have blood relatives (grandmothers, mother, sisters, aunts) on either your mother's or father's side of the family who had breast cancer diagnosed before age 50.
- There is both breast and ovarian cancer in your family, particularly in a single individual.
- There are other gland-related cancers in your family such as pancreatic, colon, and thyroid cancers.
- Women in your family have had cancer in both breasts.
- You are of Ashkenazi Jewish (Eastern European) heritage.
- You are African American and have been diagnosed with breast cancer at age 35 or younger.
- A man in your family has had breast cancer.
Source: National Cancer Institute; Healia.com
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